Rectal administration

src: i.ytimg.com

Rectal administration uses the rectum as a route of administration of drugs and other fluids, which are absorbed by the rectal blood vessels, and flows into the circulatory system of the body, which distributes drugs to the body organs. system.

Drugs administered rectally in general (drug dependent) have a faster onset, higher bioavailability, shorter peaks, and shorter duration than oral route. Another advantage of rectal administration is that it tends to produce less nausea than the oral route and prevent any amount of medication lost due to vomiting (vomiting). In addition, the rectal route passes about two-thirds of the first-pass metabolism as rectal venous drainage is the systemic two-thirds (middle and inferior rectal veins) and a third heart portal (superior rectal vein) system. This means the drug will reach the circulatory system with little change and greater concentration. Finally, rectal administration may allow patients to remain in home settings when oral routes are compromised. Unlike an intravenous line, which usually needs to be placed in an inpatient environment and requires a special formulation of sterile drugs, a special anal catheter can be placed by a doctor, such as a hospital nurse or home health nurse, at home. Many forms of oral medicines can be destroyed and suspended in water for administration through rectal catheters.

The administrative rectal route is useful for patients with gastrointestinal motility problems, such as dysphagia, ileus, or intestinal obstruction, which would interfere with drug development through the canal. This often includes patients towards the end of life (an estimated 1.65 million people are in care homes in the US each year). Because using a rectal route enables a quick, safe, and lower drug alternative to drug delivery, it can also facilitate patient care in long-term care or palliative care, or as an alternative to intravenous or subcutaneous administration in other cases..

Video Rectal administration

Method

Drug administration may be performed with any of the following:

• A suppositor, drug delivery system is inserted into the rectum.
• Enema, the action of inserting a liquid drug solution (drugs dissolved in water, the amount is usually less than 10 milliliters) into the rectum and sometimes the colon (usually when more fluid is used).
• Special catheter designed for drug administration and fluid rectally, which can be placed safely and remain comfortable in the rectum for repeated use.
• A syringe.

Maps Rectal administration

See also

• Anal disposal
• Administrative route

src: www.macycatheter.com

Note

src: i.ytimg.com

References

src: images.slideplayer.com

External links

Source of the article : Wikipedia